ANTIMICROBIAL AND ANTIVIRAL PROPERTIES
OF DIFFERENT TYPES OF PROPOLIS
1
Warsaw University of Life Sciences – SGGW
Publication date: 2021-08-09
2017;(589):69-79
KEYWORDS
ABSTRACT
Propolis is produced by bees; it is a viscous, resinous substance mainly derived
from trees, shrubs, and flower buds, enriched in wax, essential oils, pollen, and bee saliva.
The composition of propolis varies widely depending on the region of origin and vegetation
that occurs in the area, the climate, and the season in which it is produced. So far, more than
400 substances have been identified in propolis and among them are phenols, flavonoids,
phenolic acids and their esters and flavones. Propolis is divided into several types; the most
common types are poplar, European, Brazilian, and pacific propolis. Antimicrobial, antifungal, and antiviral effects of propolis have been demonstrated. Propolis inhibits Gram-positive bacteria and, to a lesser extent, Gram-negative bacteria. Propolis also inhibits the
growth of mold (Aspergillus and Penicillium) and yeast (Candida). The antiviral activity
of propolis against poliovirus, influenza A and B viruses, reoviruses, and HIV has been
demonstrated.
REFERENCES (50)
1.
Adomaviciute E., Stanys S., Cilius M., Juškait V., Pavilonis A., Briedis V., 2016. Formation and Biopharmaceutical Characterization of Electrospun PVP Mats with Propolis and Silver Nanoparticles for Fast Releasing Wound Dressing. Biomed Res. Int. http://dx.doi.org/10.1155/2016....
2.
Baltas N., Karaoglu S.A., Tarakci C., Kolayli S., 2016. Effect of propolis in gastric disorders: inhibition studies on the growth of Helicobacter pylori and production of its urease. J. Enzyme Inhib. Med. Chem. 31(S2), 46–50.
3.
Bankova V., 2005. Chemical diversity of propolis and the problem of standardization. J. Ethnopharmacol. 100, 114–117.
4.
Bankova V., Popova M., Trusheva B., 2016. New emerging fields of application of propolis. Maced. J. Chem. Chem. Eng. 35(1), 1–11.
5.
Benhanifia M., Shimomura K., Tsuchiya I., Inui S., Kumazawa S., Mohamed W.M., Boukraa L., Sakharkar M.K., Benbarek H., 2014. Chemical composition and antimicrobial activity of propolis collected from some localities of western Algeria. Acta Aliment. 43(3), 482–488.
6.
Boufadi Y.M., Soubhye J., Neve J., Van Antwerpen P., Riazi A., 2016. Antimicrobial effects of six Algerian propolis extracts. Int. J. Food Sci. Technol. 51, 2613–2620.
7.
Boyanova L., Derejian S., Koumanova R., Katsarov N., Gergova G., Mitov I., Nikolov R., Krastev Z., 2003. Inhibition of Helicobacter pylori growth in vitro by Bulgarian propolis: preliminary report. J. Med. Microbiol. 52, 417–419.
8.
Bryan J., Redden P., Traba C., 2015. The mechanism of action of Russian propolis ethanol extracts against two antibiotic-resistant biofilm-forming bacteria. Lett. Appl. Microbiol. 62, 192–198.
9.
Búfalo M.C., Figueiredo A.S., de Sousa J.P., Candeias J.M., Bastos J.K., Sforcin J.M., 2009. Antipoliovirus activity of Baccharis dracunculifolia and propolis by cell viability determination and real-time PCR. J. Appl. Microbiol. 107(5), 1669–1680.
10.
Burdock G.A., 1998. Review of the biological properties and toxicity of bee propolis (propolis). Food Chem. Toxicol. 36, 347–363.
11.
Cantarelli M.A., Caminia J.M., Pettenati E.M., Marchevsky E.J., Pellerano R.G. (2011) Trace mineral content of Argentinean raw propolis by neutron activation analysis (NAA): Assessment of geographical provenance by chemometrics. J. Food Sci. Technol. 44, 256–260.
12.
Cardoso R.L., Maboni F., Machado G., Alves S.H., de Vargas A.C. (2010) Antimicrobial activity of propolis extract against Staphylococcus coagulase positive and Malassezia pachydermatis of canine otitis. Vet. Microbiol. 142, 432–434.
13.
Chasset T., Häbe T.T., Ristivojevic P., Morlock G.E., 2016. Profiling and classification of French propolis by combined multivariate data analysis of planar chromatograms and scanning direct analysis in real time mass spectra. J. Chromatogr. A 1465, 197–204.
14.
Choi Y.M., Noh D.O., Cho S.Y., Suh H.J., Kim K.M., Kim J.M., 2006. Antioxidant and antimicrobial activities of propolis from several regions of Korea. LWT Food Sci. Technol. 39, 756–761.
15.
De Groot A.C., Popova M.P., Bankova V.S., 2014. An update on the constituents of poplar-type propolis. Wapserveen, The Netherlands.
16.
Dziedzic A., Kubina R., Wojtyczka R.D., Kabała-Dzik A., Tanasiewicz M., Morawiec T., 2013. The Antibacterial Effect of Ethanol Extract of Polish Propolis on Mutans Streptococci and Lactobacilli Isolated from Saliva. Evid. Based Complement. Alternat. Med., ID 681891.
17.
Ertürk Ö., Çil E., Yoloğlu N., Yavuz C., 2016. An In vitro Study on Antimicrobial and Antioxidant Activity of Propolis from Rize Province of Turkey. Mellifera 16(1), 4–18.
18.
Fernandes-Silva C.C., Salatino A., Salatino M.L.F., Breyer E.D.H., Negri D., 2013. Chemical profiling of six samples of brazilian propolis. Quim. Nova 36 (2), 237–240.
19.
Freires I.A., Queiroz V.C.P.P., Furletti V.F., Ikegaki M., de Alencar S.M., Duarte M.C.T., Rosalen P.L., 2016. Chemical composition and antifungal potential of Brazilian propolis against Candida spp. J. Mycol. Med. 26, 122–132.
20.
Garedew A., Schmolz E., Lamprecht I., 2004. Microbiological and calorimetric investigations on the antimicrobial actions of different Propolis extracts: an in vitro approach. Thermochim. Acta 422, 115–124.
21.
Gekker G., Hu S., Spivak M., Lokensgard J.R., Peterson P.K., 2005. Anti-HIV-1 activity of propolis in CD4 + lymphocyte and microglial cell cultures. J. Ethnopharmacol. 102(2), 158–163.
22.
Ghaly M.F., Ezzat S.M., Sarhan M.M., 1998. Use of propolis and ultragriseofulvin to inhibit aflatoxigenic fungi. Folia Microbiologica 43(2), 156–160.
23.
Gomes do Nascimento T., Fonseca da Silva P., Azevedo L.F., Guerra da Rocha L., Celerino de Moraes Porto I.C., Accioly Lima e Moura T.F., Basílio-Júnior I.D., Aparecido Meireles Grillo L., Braga Dornelas C., da Silva Fonseca E.J., de Jesus Oliveira E., Zhang A.T., Watson D.G., 2016. Polymeric Nanoparticles of Brazilian Red Propolis Extract: Preparation, Characterization, Antioxidant and Leishmanicidal Activity. Nanoscale Res. Lett. 11, 301, doi 10.1186/s11671-016-1517-3.
24.
Graikou K., Popova M., Gortzi O., Bankova V., Chinou I., 2016. Characterization and biological evaluation of selected Mediterranean propolis samples. Is it a new type? LWT Food Sci. Technol. 65, 261–267.
25.
Haung S., Zhang C., Wang K., Li G., Hu F.L., 2014. Recent advances in the chemical composition of propolis. Molecules 19(12), 19610–19632.
26.
Kalogeropoulos N., Spyros K., Troullidou J., Mourtzinos E., Karathanos I., Vaios T., 2009. Chemical composition, antioxidant activity and antimicrobial properties of propolis extracts from Greece and Cyprus. Food Chem.116(2), 452–461.
27.
Kubiliene L., Laugaliene V., Pavilonis A., Maruska A., Majiene D., Barcauskaite K., Kubilius R., Kasparaviciene G., Savickas A., 2015. Alternative preparation of propolis extracts: comparison of their composition and biological activities. BMC Complement. Altern. Med. 15, 156.
28.
Lopez B.G.-C., de Lourenco C.C., Alves D.A., Machado D., Lancellotti M., Sawaya A.C.H.F., 2015. Antimicrobial and cytotoxic activity of red propolis: an alert for its safe use. J. Appl. Microbiol. 119, 677–687.
29.
Marcucci M.C., 1995. Propolis: chemical composition, biological properties and therapeutic activity. Apidologie 26, 83−99.
30.
Mendonça L.S., Mendonça F.M.R., Araújo Y.L.F.M., Araújo E.D., Ramalho S.A., Narain N., Jain S., Orellana S.C., Padilha F.F., Cardoso J.C., 2015. Chemical markers and antifungal activity of red propolis from Sergipe, Brazil. Food Sci. Technol. (Campinas) 35(2), 291–298.
31.
Meneses E.A., Durango D.L., García C.M., 2009. Antifungal activity against postharvest fungi by extracts from Colombian propolis. Quim. Nova 32(8), 2011–2017.
32.
Milojkovic-Opsenica D., Ristivojevic P., Trifkovic J., Vovk I., Lušic D., Tešic Ž., 2016. TLC Fingerprinting and Pattern Recognition Methods in the Assessment of Authenticity of Poplar-Type Propolis. J. Chromatogr. Sci. 54(7), 1077–1083.
33.
Mirzoeva O.K., Grishanin R.N., Calder P.C., 1997. Antimicrobial action of propolis and some of its components: the effects on growth, membrane potential and motility of bacteria. Microbiol. Res. 152, 239–246.
34.
Morlock G.E., Ristivojevic P., Chernetsova E.S., 2014. Combined multivariate data analysis of high-performance thin-layer chromatography fingerprints and direct analysis in real time mass spectra for profiling of natural products like propolis. J. Chromatogr. A, 1328, 104–112.
35.
Negri G., Marcucci C., Salatino A., Salatino M.L.F., 2000. Comb and propolis waxes from Brazil. J. Braz. Chem. Soc.11, 453–457.
36.
Peng L., Yang S., Cheng Y.J., Chen F., Pan S., Fan G., 2012. Antifungal activity and action mode of pinocembrin from propels against Penicillium italicum. Food Sci. Biotechnol. 21(6), 1533–1539.
37.
Pippi B., Lana A.J.D., Moraes, R.C. Güez C.M., Machado M., de Oliveira L.F.S., Lino von Poser G., Fuentefria A.M., 2015. In vitro evaluation of the acquisition of resistance, antifungal activity and synergism of Brazilian red propolis with antifungal drugs on Candida spp. J. Appl. Microbiol. 118, 839–850.
38.
Ristivojević P., Dimkić I., Trifković J., Berić T., Vovk I., Milojković-Opsenica D., Stanković S., 2016. Antimicrobial Activity of Serbian Propolis Evaluated by Means of MIC, HPTLC, Bioautography and Chemometrics. PLoS ONE 11(6), 1–15.
39.
Ristivojević P., Trifković J., Andrić F., Milojković-Opsenica D., 2015. Poplar-type Propolis: Chemical Composition, Botanical Origin and Biological Activity. Nat. Prod. Commun. 10(11), 1869–1876.
40.
Sapieha-Waszkiewicz A., Marjańska-Cichoń B., Miętkiewski R., 2011. Effect of biopesticides on the growth and development of isolates of Botrytis cinerea Pers., in vitro obtained from raspberry plants. J. Plant Prot. Res. 51(2), 151–156.
41.
Scazzocchio F., D’Auria F.D., Alessandrini D., Pantanella F., 2006. Multifactorial aspects of antimicrobial activity of propolis. Microbiol. Res. 161, 327–333.
42.
Schnitzler P., Neuner A., Nolkemper S., Zundel Ch., Nowack H., Sensch K.H., Reichling J., 2011. Antiviral Activity and Mode of Action of Propolis Extracts and Selected Compounds. Phytother. Res. 24, S20–S28.
43.
Shimizu T., Hino A., Tsutsumi A., Park YK., Watanabe W., Kurokawa M., 2008. Anti-influenza virus activity of propolis in vitro and its efficacy against influenza infection in mice. Antiviral Chem. Chemother. 19(1), 7–13.
44.
Takasi K., Kikuni N.B., Schiller H., 1994. Electron microscopic and microcalorimetric investigations of the possible mechanism of the antibacterial action of propolis. Provenance Planta Med. 60, 222–227.
45.
Tegos G., Stermitz F.R., Lomovskaya O., Lewis K., 2002. Multidrug pump inhibitors uncover remarkable activity of plant antimicrobials. Antimicrob. Agents Chemother. 46, 3133–3141.
46.
Temiz A., Mumcu A.S., Tüylü A.Ö., Sorkun K., Salih B., 2013. Antifungal activity of propolis samples collected from different geographical regions of Turkey against two food-related molds, Aspergillus versicolor and Penicillium aurantiogriseum. GIDA 38(3), 135–142.
47.
Waldner-Tomic N.M., Vanni R., Belibasakis G.N., Thurnheer T., Attin T., Schmidlin P.R., 2014. The in Vitro Antimicrobial Efficacy of Propolis against Four Oral Pathogens: A Review. J. Dentistry 2, 85–97.
48.
Weinstein T.E., Negri G., Meira R.M.S.A., Massage D., Salatino A., 2005. Plant origin of green propolis: bee behavior, plant anatomy and chemistry. Evid. Based Complement. Alternat. Med. 2(1), 85–92.
49.
Woźniak M., Ratajczak I., Kwaśniewska P., Cofta G., Hołderna-Kędzia E., Kędzia B., Mazela B., 2015. The activity of propolis extracts against selected moulds [Badanie aktywności ekstraktów propolisowych wobec wybranych gatunków grzybów pleśniowych]. Postępy Fitoterapii 4, 205–209.
50.
Yildirim A., Duran G.G., Duran N., Jenedi K., Bolgul B.S., Miraloglu M., Muz M., 2016. Antiviral Activity of Hatay Propolis Against Replication of Herpes Simplex Virus Type 1 and Type 2. Med. Sci. Monit. Basic Res. 22, 422–430.
| ISSN: | 0084-5477 |
We process personal data collected when visiting the website. The function of obtaining information about users and their behavior is carried out by voluntarily entered information in forms and saving cookies in end devices. Data, including cookies, are used to provide services, improve the user experience and to analyze the traffic in accordance with the Privacy policy. Data are also collected and processed by Google Analytics tool (more).
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.
You can change cookies settings in your browser. Restricted use of cookies in the browser configuration may affect some functionalities of the website.
