Measurements of the destruction time of the sediment column structure of silica particles were carried out for different fractions of silica particles in alkanes from decane to hexadecane. The authors studied the correlations between the measured destruction time of the silica particles sediment column structure and the bulk properties of silica particles and alkanes, as well as the alkane-air, silica particles-air and silica particles-alkane interfacial properties. On the basis of this study linear relationships between the reciprocal of the destruction time and the average diameter of the silica particles fractions, the work of alkanes cohesion, the alkanes density and the difference between the detachment and attachment forces were found. From these relationships, the critical values of the particle diameter, the cohesion work of the alkane density and the difference between the detachment and the attachment forces were determined. It was found that for the systems, having critical values of the parameters mentioned above, the detachment force is equal to the attachment force, both resulting from gravitational and interfacial interactions, respectively. It also results from the present study that the attachment force between silica particles depends on the work of alkane cohesion and the work of silica particle adhesion to liquid, and that destruction of silica particles sediment column structure takes place as a result of interruption of the alkane film between two silica particles. The changes of the destruction time as a function of the number of carbon atoms in the molecule of alkanes occurred as a result of the decreased detachment force and the perimeter of the contact plane and increased attachment force between silica particles in alkanes.