In recent years, with the deepening of the degree of coal mining and the improvement of the mechanization and intelligent level of coal dressing, the proportion of fine and micro-fine coal production has been increasing. Micro-fine grade separation has gradually become an important research direction in coal washing industry. This paper is based on a novel jet-stirring synergistic column flotation method, which integrates jet-impact mixing, impeller mixing, and dispersion into the structure of a column flotation tank. By combining with existing research foundations, we construct a corresponding physical model and conduct optimization studies on key parameters related to jetting, impeller mixing, and mechanism. The resulting fundamental theory provides clear insights for the engineering application of this innovative flotation technology. The effects of jet-stirring synergy on bubble adsorption and reagent adsorption were studied, and the flotation effect of the new flotation technology was experimentally verified, laying a theoretical foundation for the industrial application of the device.