A series of surfactant mixtures which consist of DAH (dodecylamine hydrochloride) and fatty acids (FAD) were made in this study. The characteristics of these fatty acids/DAH mixtures, including surface tension, critical micelle concentration (CMC) and adsorption onto coal were investigated. The reverse flotation results with these fatty acids/DAH mixtures (FAD) and DAH were compared with each other. Experimental results showed that the fatty acids/ DAH mixtures have lower CMC and γcmc than DAH. The adsorption test indicated that more amine molecules would adsorb preferentially onto the bubbles surface in FAD solutions than that in DAH solutions. Reverse flotation results showed that about 50% surfactant dosage was saved under the same froth product yield. Only 28% froth product yield was obtained in the presence of 1.66 kg/Mg DAH. However, when 0.83 kg/Mg hexadecanoic acid/DAH mixture (C16D) surfactant was used, the froth product yield reached 29%. Dodecanoic acid/DAH mixture (C12D) surfactant a showed better performance with a high mineral matter recovery similar to that with tetradecanoic acid/DAH mixture (C14D) and higher combustible recovery than with C14D and C16D.